Psoriasis is a chronic skin condition resulting from an overactive immune system that causes skin cells to multiply rapidly, leading to red, itchy, and scaly patches on the skin.

Traditional Treatments

For many years, traditional treatments such as topical creams, light therapy, and systemic medications have been used to manage and treat psoriasis symptoms.

While these treatments can be effective, they often come with side effects and may not work for everyone.

Targeted Treatments

In recent years, there has been a shift towards developing targeted treatments for psoriasis.

These treatments aim to specifically target the immune system cells and cytokines that contribute to psoriasis symptoms, without affecting the rest of the immune system.

Biologics

Biologic drugs are a form of targeted treatment that work by blocking specific cytokines that contribute to inflammation in psoriasis. These drugs are given via injection or infusion and are usually reserved for more severe cases of psoriasis.

Commonly prescribed biologics for psoriasis include adalimumab, etanercept, and ustekinumab.

JAK Inhibitors

Janus kinase (JAK) inhibitors are another type of targeted treatment that work by blocking an enzyme involved in the immune response. This helps to reduce inflammation and slow down the production of skin cells in psoriasis.

JAK inhibitors come in pill form and include drugs such as baricitinib and tofacitinib.

Topical Targeted Treatments

Targeted treatments can also come in the form of topical creams or ointments. These creams work by targeting specific immune cells or proteins involved in psoriasis.

One example of a topical targeted treatment is calcitriol, which works by regulating the growth and division of skin cells.

Combination Therapy

While targeted treatments can be effective on their own, they may be even more effective when combined with other psoriasis treatments.

For example, combining a biologic drug with light therapy may help to reduce the amount of time spent on phototherapy and improve overall symptom control.

Conclusion

Targeted treatments for psoriasis offer a promising new approach to managing this chronic skin condition.

Whether used alone or in combination with traditional treatments, these treatments offer a more targeted approach to reducing symptoms and improving quality of life for those living with psoriasis.