Psoriasis is a chronic skin condition that causes cells to build up rapidly on the surface of the skin. It affects approximately 7.5 million people in the United States.

There are a number of different medications available to treat psoriasis, but recent research has shown that some of these medications may be linked to increased health risks.

Methotrexate

Methotrexate is a medication commonly used to treat psoriasis. It works by suppressing the immune system, which can help to reduce inflammation in the skin.

While methotrexate can be effective for some patients, it also comes with a number of potential health risks.

One of the most serious risks associated with methotrexate is liver damage. The drug can cause inflammation and scarring in the liver, which can lead to cirrhosis or liver failure.

Methotrexate can also cause gastrointestinal problems, such as nausea and vomiting. Some patients may develop mouth ulcers or sores as a result of using methotrexate.

Biologic Medications

Biologic medications are a newer class of drugs that are often used to treat psoriasis. They work by targeting specific parts of the immune system that are involved in the development of psoriasis.

While biologics can be effective for some patients, they also come with a number of potential risks.

One of the most serious risks associated with biologics is an increased risk of infections. Because these drugs suppress the immune system, patients taking biologics may be more susceptible to infections.

Biologics have also been linked to an increased risk of certain types of cancer, including skin cancer and lymphoma.

Corticosteroids

Corticosteroids are a type of medication that is often used to treat psoriasis. They work by reducing inflammation in the skin. While corticosteroids can be effective in treating psoriasis, they also come with a number of potential risks.

One of the most serious risks associated with corticosteroids is thinning of the skin. Prolonged use of corticosteroids can cause the skin to become thin and fragile, which can lead to cuts and bruises.

Corticosteroids can also increase the risk of infections and may cause other side effects such as acne, weight gain, and mood changes.

Conclusion

While there are a number of medications available to treat psoriasis, it is important for patients to be aware of the potential risks associated with these drugs.

Patients should work closely with their doctor to weigh the potential benefits and risks of each medication and develop a treatment plan that is right for them.