Aspirin has been a widely used drug for centuries to reduce fevers and relieve pain. However, in recent years, it has become an important topic of discussion for its potential to prevent certain types of cancers, including ovarian cancer.

In this article, we will explore the link between aspirin and the prevention of this deadly disease.

Understanding Ovarian Cancer

Ovarian cancer is a type of cancer that affects the ovaries, which are the female reproductive organs that produce eggs.

Despite being a relatively rare form of cancer, ovarian cancer accounts for 3% of all cancers in women and is the fifth leading cause of cancer-related deaths in women.

Some of the symptoms of ovarian cancer include:.

Abdominal swelling or bloating
Pain or discomfort in the pelvic area
Difficulty eating or feeling full quickly
Urinary symptoms, such as urgency or frequency

While there is no sure way to prevent ovarian cancer, there are some risk factors that increase a woman’s chances of developing the disease. These risk factors include:.

Family history of ovarian cancer
Personal history of breast, uterine, or colon cancer
Genetic mutations, such as BRCA1 or BRCA2
Advanced age
Obesity
Use of fertility treatments

Aspirin and Cancer Prevention

Aspirin belongs to a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs), which work by blocking an enzyme called COX-2 that is involved in inflammation and pain.

Over the years, studies have shown that aspirin and other NSAIDs have anti-cancer properties, particularly in preventing colorectal cancer.

Researchers believe that aspirin may help prevent cancer by:.

Reducing inflammation in the body
Inhibiting the growth of tumor cells
Preventing the formation of blood vessels that feed tumors
Reducing the production of hormones that can contribute to the growth of some cancers

Aspirin and Ovarian Cancer

While most of the research on aspirin and cancer prevention has focused on colorectal cancer, there is a growing body of evidence suggesting that aspirin may also be effective in preventing ovarian cancer.

A study published in the Journal of the National Cancer Institute in 2014 found that women who took low-dose aspirin (81mg) at least twice a week had a 23% lower risk of ovarian cancer compared to those who did not take aspirin.

The study also found that women who took aspirin for longer periods of time had a greater risk reduction.

Another study published in the Journal of the American Medical Association in 2018 found that women who took low-dose aspirin for at least six years had a 20% lower risk of developing ovarian cancer.

While these studies suggest a potential link between aspirin and ovarian cancer prevention, it is important to note that more research is needed to confirm these findings.

Additionally, aspirin may not be appropriate for everyone, as it can increase the risk of bleeding, especially in individuals with a history of gastrointestinal ulcers or bleeding disorders. Therefore, it is essential to speak with a healthcare professional before taking aspirin for cancer prevention.

Other Ways to Reduce the Risk of Ovarian Cancer

In addition to aspirin, there are other steps women can take to reduce their risk of ovarian cancer. These include:.

Eating a healthy diet that is high in fruits and vegetables and low in fat
Exercising regularly
Using contraception, which has been shown to reduce the risk of ovarian cancer
Having children at a younger age
Undergoing risk-reducing surgery for high-risk individuals

The Bottom Line

Ovarian cancer is a serious disease that can be difficult to detect and treat. While there is no sure way to prevent it, aspirin may play a role in reducing the risk of developing the disease.

However, more research is needed to confirm these findings, and it is important to speak with a healthcare professional before taking aspirin for cancer prevention.