Cervical cancer is a type of cancer that occurs in the cells of the cervix, which is the lower part of the uterus that connects to the vagina.
According to the World Health Organization (WHO), cervical cancer is the fourth most common cancer among women worldwide, with an estimated 570,000 new cases and 311,000 deaths in 2018. However, there is now some great news for women suffering from cervical cancer. A revolutionary new treatment called immunotherapy is providing hope for those battling this deadly disease.
What is Immunotherapy?
Immunotherapy is a type of cancer treatment that enhances your body’s natural defenses or immune system to fight cancer cells.
Unlike traditional cancer therapies such as chemotherapy and radiation, which kill both cancer and healthy cells, immunotherapy targets only cancer cells, leaving healthy cells intact.
Immunotherapy works by stimulating the immune system to recognize cancer cells as foreign invaders and attack them.
It does this by using substances such as antibodies, cytokines, and cancer vaccines to target specific proteins on cancer cells or boost the immune system’s response to cancer cells.
How Immunotherapy is Curing Cervical Cancer
Immunotherapy has shown great promise in the treatment of cervical cancer. This type of cancer is caused by the human papillomavirus (HPV), which is a sexually transmitted virus.
HPV changes the DNA of cells in the cervix, leading to the uncontrolled growth and division of abnormal cells that can lead to cancer.
Until recently, the standard treatments for cervical cancer included surgery, radiation therapy, and chemotherapy. While these treatments can be effective, they often come with side effects that can be severe and debilitating.
In addition, the chances of survival for cervical cancer patients that don’t respond well to these treatments are poor.
Immunotherapy has been found to be a game-changer for cervical cancer patients.
In a groundbreaking clinical study published in the Journal of Clinical Oncology, researchers found that a combination of two immunotherapy drugs, ipilimumab and nivolumab, was able to shrink tumors in half of the patients with advanced cervical cancer and keep the cancer from growing for more than six months in 80% of patients.
In another study published in The Lancet Oncology, researchers used an immunotherapy vaccine to target HPV16 and HPV18, the two strains of HPV that cause 70% of cervical cancer cases.
The vaccine stimulated the immune system to produce T-cells, which are white blood cells that can recognize and destroy cancer cells. The study found that the vaccine was able to eliminate pre-cancerous lesions in 25% of women with early-stage cervical cancer.
Benefits and Limitations of Immunotherapy for Cervical Cancer
Immunotherapy has several benefits over traditional cancer treatments for cervical cancer patients. It is less toxic and can be given in higher doses than chemotherapy or radiation.
It is also more targeted, meaning that it can attack cancer cells more precisely and leave healthy cells unaffected. In addition, many patients experience fewer side effects with immunotherapy than with traditional therapies.
However, there are some limitations to immunotherapy for cervical cancer. Some patients may not respond to the treatment, and it can be expensive. In addition, immunotherapy can cause side effects, including fatigue, nausea, diarrhea, and itching.
How to Access Immunotherapy for Cervical Cancer Patients
Immunotherapy is currently available through clinical trials and as part of standard cancer treatment for certain types of cancer, including melanoma and lung cancer. However, it is not yet a standard treatment option for cervical cancer.
Women with cervical cancer who are interested in immunotherapy should talk to their doctors to see if they are eligible for a clinical trial or if there are any other treatment options available.
It is also important to work with a healthcare team that is experienced in treating cervical cancer to ensure the best possible outcome.
Conclusion
Immunotherapy is a groundbreaking new treatment that is providing hope for people with many types of cancer, including cervical cancer. While more research is needed to fully understand its potential, the early results are promising.
By stimulating the body’s natural immune system to fight cancer, immunotherapy offers a less toxic, more targeted, and potentially more effective treatment option for women with cervical cancer.