This article explores the effects of BMI on survival in Multiple Myeloma Patients. Multiple myeloma is a type of cancer that affects the bone marrow, causing the plasma cells to become cancerous and overproduce.

BMI or Body Mass Index, is a measure of body fat based on height and weight.

The Study

Multiple studies have been conducted to investigate the link between BMI and survival in multiple myeloma patients. A recent study conducted by the Mayo Clinic analyzed 550 Multiple Myeloma patients over a period of 10 years.

Results

The study found that patients with a BMI of 30 or above had better overall survival rates compared to those with a BMI of less than 25.

The study also showed that patients who lost weight during treatment had worse outcomes compared to those who maintained their weight or gained weight.

Possible Explanations

The reasons for this correlation between BMI and survival in Multiple Myeloma patients are not yet clear, but several theories have been suggested. Obese individuals may have higher levels of certain immune cells, which may help to fight the cancer.

In addition, obese individuals may have higher levels of growth factors such as leptin, which may help to promote healthy bone marrow function.

On the other hand, underweight individuals may have weakened immune systems, which may make them more susceptible to complications and infections.

They may also have lower levels of growth factors such as estradiol, which may lead to impaired bone growth and repair.

Conclusion

The correlation between BMI and survival in Multiple Myeloma patients is an interesting area of research, and more studies are needed to determine the reasons behind this correlation.

Nevertheless, maintaining a healthy BMI may be beneficial for Multiple Myeloma patients, and weight loss during treatment should be carefully monitored.