Ovarian removal, also known as oophorectomy, is a surgical procedure that involves the removal of one or both ovaries. This procedure is usually performed to treat conditions such as ovarian cancer, ovarian cysts, and endometriosis.
However, the removal of ovaries also affects the risk of developing other types of cancers in women. This article will explore the link between ovarian removal and cancer risk.
Ovarian Removal and Cancer Risk
Studies have shown that women who have had their ovaries removed have a reduced risk of developing ovarian cancer.
This is because ovarian cancer is usually caused by abnormal cell growth in the ovaries, and by removing the ovaries, the risk of this abnormal cell growth is significantly reduced.
However, the removal of ovaries can also increase the risk of developing other types of cancers, such as breast cancer and colorectal cancer.
This is because the ovaries produce estrogen and other hormones that are important for the normal functioning of the body. When the ovaries are removed, the body’s levels of estrogen and other hormones decrease, which can affect the risk of developing certain types of cancers.
Types of Ovarian Removal
There are two types of ovarian removal: unilateral oophorectomy and bilateral oophorectomy.
Unilateral Oophorectomy
Unilateral oophorectomy involves the removal of one ovary. This procedure is usually performed to treat conditions such as ovarian cysts or endometriosis.
Women who have had a unilateral oophorectomy have a slightly reduced risk of developing ovarian cancer, but their overall risk of cancer is not significantly affected.
Bilateral Oophorectomy
Bilateral oophorectomy involves the removal of both ovaries. This procedure is usually performed to treat conditions such as ovarian cancer or to reduce the risk of developing ovarian cancer in women who are at high risk.
Women who have had a bilateral oophorectomy have a significantly reduced risk of developing ovarian cancer, but their risk of other types of cancers may be increased.
Impact on Breast Cancer Risk
The ovaries produce estrogen and other hormones that are important for the normal functioning of the body. When the ovaries are removed, the body’s levels of these hormones decrease.
This decrease in hormone levels can affect the risk of developing certain types of cancers, such as breast cancer.
Studies have shown that women who have had a bilateral oophorectomy have an increased risk of developing breast cancer, especially if they have a family history of breast cancer or a genetic mutation that increases the risk of breast cancer, such as the BRCA1 or BRCA2 gene mutation.
However, the risk of developing breast cancer after ovarian removal varies depending on several factors, including the age at which the ovaries were removed and whether or not the woman has undergone hormone replacement therapy.
Impact on Colorectal Cancer Risk
The ovaries also produce hormones that can affect the risk of developing colorectal cancer. When the ovaries are removed, the body’s levels of these hormones decrease, which can increase the risk of developing colorectal cancer.
Studies have shown that women who have had a bilateral oophorectomy have an increased risk of developing colorectal cancer, especially if they have a family history of colorectal cancer or a personal history of bowel disease.
Hormone Replacement Therapy
Some women may choose to undergo hormone replacement therapy (HRT) after ovarian removal to replace the hormones that their body is no longer producing.
However, HRT has been shown to increase the risk of developing breast cancer and other types of cancers, so it is important for women to discuss the risks and benefits of HRT with their doctor.
Women who have undergone ovarian removal should also be vigilant about other risk factors for cancer, such as smoking, obesity, and a poor diet.
They should also undergo regular cancer screenings, such as mammograms and colonoscopies, to detect any cancers early.
Conclusion
Ovarian removal can affect the risk of developing certain types of cancer in women. While the risk of ovarian cancer is significantly reduced after ovarian removal, the risk of breast cancer and colorectal cancer may be increased.
Women who undergo ovarian removal should discuss their cancer risk with their doctor and take steps to reduce their overall risk of cancer.