Cholesterol is one of the essential substances required by our body for the synthesis of hormones and vitamin D. Cholesterol is naturally produced by our liver and is also obtained from the food we consume.
There are mainly two types of cholesterol – LDL (Low-Density Lipoproteins) and HDL (High-Density Lipoproteins). LDL cholesterol is often referred to as the “bad” cholesterol as it is responsible for clogging arteries and increasing the risk of heart diseases.
On the other hand, HDL cholesterol is deemed as the “good” cholesterol as it helps remove excess cholesterol from the arteries and reduces the risk of heart diseases. However, is good cholesterol really good for you? This article will discuss in detail whether HDL is actually beneficial for our health.
Understanding HDL Cholesterol
HDL (High-Density Lipoproteins) cholesterol is commonly referred to as “good” cholesterol due to its various health attributes.
HDL cholesterol is a type of lipoprotein that plays a crucial role in transporting cholesterol molecules from the bloodstream to the liver, where it is excreted from the body. Hence, HDL is responsible for removing excess cholesterol from the bloodstream, preventing the build-up of plaques in the arteries that can lead to heart diseases, stroke, and other health issues.
HDL is synthesized in the liver and small intestine and is composed of proteins, lipids, and triglycerides. HDL molecules are smaller in size and denser than other lipoproteins, making them more efficient in carrying cholesterol molecules.
HDL cholesterol levels are usually increased by consuming a healthy diet, exercising regularly, quitting smoking, and maintaining a healthy weight.
The Relation between HDL Cholesterol and Heart Diseases
The importance of HDL cholesterol in reducing the risk of heart diseases cannot be overstressed.
High levels of HDL cholesterol are associated with lower rates of heart disease, while low levels of HDL can increase the risk of heart diseases and other cardiovascular events. Studies have shown that every 1 mg/dL increase in HDL cholesterol levels lowers the risk of heart diseases by 2-3%.
Moreover, a study conducted by Harvard Medical School found that every 1% increase in HDL cholesterol levels could reduce the risk of heart disease by 2-4%.
However, despite the numerous studies linking HDL cholesterol to reduced risk of heart diseases, the relationship between HDL and heart health is not as straightforward as it seems.
Some clinical trials and research have challenged the idea of HDL cholesterol as the “good” cholesterol, stating that raising HDL levels alone may not provide the desired results in reducing the risk of heart diseases.
The Dark Side of HDL Cholesterol
Recent research has shown that HDL cholesterol is not always beneficial for our health. In some cases, HDL cholesterol can also contribute to heart diseases and other health issues in the body. Here are some of the negative aspects of HDL cholesterol:.
HDL Cholesterol can Become Dysfunctional
Research has suggested that the protective effects of HDL cholesterol depend on its function, not its levels.
HDL cholesterol can lose its cardioprotective properties and become dysfunctional under certain conditions, such as inflammation, oxidative stress, and metabolic disorders. Dysfunctional HDL cholesterol is incapable of removing excess cholesterol from the bloodstream, and instead, contributes to the formation of plaques in the arteries, leading to heart diseases.
HDL Cholesterol can Increase Inflammation
HDL cholesterol is typically known for its anti-inflammatory properties, but under certain conditions, it can also promote inflammation.
Oxidized HDL cholesterol, which occurs due to low antioxidant capacity, promotes inflammatory responses in the arteries, leading to the development of atherosclerosis and heart diseases.
Higher HDL Levels do not Always Reflect Better Health
As discussed earlier, HDL cholesterol is often referred to as the “good” cholesterol, and the higher the HDL levels, the better. However, some studies have shown that extremely high HDL levels may not be as beneficial as previously thought.
In a study published in the European Heart Journal, individuals with extremely high HDL levels (above 90 mg/dL) were found to be at a higher risk of heart diseases than those with moderately elevated HDL levels (60-80 mg/dL).
: Conclusion
While HDL cholesterol is considered essential for reducing the risk of heart diseases, it is not always beneficial for our health. The protective effects of HDL cholesterol depend on its function and quality, not just its quantity.
Exercise, a healthy diet, quitting smoking, and maintaining a healthy weight can help increase HDL levels and improve its quality. However, excessively elevated HDL levels may not always result in better health outcomes. Hence, it is crucial to maintain a balanced and healthy lifestyle to ensure overall well-being and reduce the risk of heart diseases and other health issues.