During pregnancy, it’s crucial to be vigilant about the medications you take. Many drugs can potentially harm the developing fetus and result in birth defects or other complications.

To ensure the safety of both mother and baby, it is important to avoid certain medications during pregnancy. This article provides an overview of medications that should be avoided and highlights safer alternatives.

1. Accutane and other Retinoids

Accutane, a commonly prescribed medication for severe acne, is known to cause severe birth defects. It is classified as a pregnancy category X drug, indicating that it should be entirely avoided during pregnancy.

Other retinoids, such as tretinoin and adapalene, should also be avoided due to their potential to harm the fetus.

2. ACE Inhibitors

ACE inhibitors, drugs commonly used for treating high blood pressure, can cause kidney damage and negatively impact fetal development.

These medications should be discontinued as soon as a pregnancy is suspected, and alternative therapies should be explored under close medical supervision.

3. Ibuprofen and Aspirin

Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and aspirin should be avoided during pregnancy, especially during the third trimester.

These drugs can increase the risk of complications, including premature closure of the fetal ductus arteriosus, which can lead to pulmonary hypertension in the newborn.

4. Warfarin

Warfarin, an anticoagulant used to prevent blood clotting, is known to cross the placenta and can cause severe bleeding and malformations in the fetus.

Pregnant women requiring anticoagulation are usually switched to heparin, which has a more favorable safety profile during pregnancy.

5. Methotrexate

Methotrexate, a medication used to treat certain cancers and autoimmune disorders, is contraindicated during pregnancy due to its potential to cause birth defects.

This drug should be discontinued well in advance of attempting pregnancy, and alternative treatment options should be discussed with a healthcare provider.

6. Tetracycline

Tetracycline antibiotics, including doxycycline and minocycline, can interfere with fetal bone development and discolor permanent teeth. They should be avoided during pregnancy, especially during the second and third trimesters.

Alternative antibiotics can be prescribed when necessary.

7. Valproic Acid

Valproic acid, an anti-seizure medication also used for bipolar disorder and migraine prevention, can increase the risk of neural tube defects and developmental delays.

Pregnant women taking valproic acid should speak with their healthcare provider to explore safer alternatives.

8. Statins

Statins, commonly prescribed for lowering cholesterol levels, should not be taken during pregnancy due to potential adverse effects on the developing fetus.

Women of reproductive age who require cholesterol management should discuss alternative strategies with their healthcare provider.

9. Lithium

Lithium, a medication used to treat bipolar disorder, can lead to heart defects and other malformations if taken during pregnancy.

However, abruptly discontinuing lithium can have adverse effects on a woman’s mental health, so it is crucial to consult with a healthcare provider before stopping or adjusting any medication.

10. Herbal Supplements

While herbal supplements are often considered natural, they can still pose risks during pregnancy. Many herbs have not been rigorously studied for their safety during pregnancy, and some may cause complications.

It is best to consult with a healthcare provider before taking any herbal supplements during pregnancy.