Pancreatic cancer is one of the deadliest forms of cancer, with a five-year survival rate of only about 10%. One of the reasons pancreatic cancer is so deadly is that it is often not detected until it has reached an advanced stage.
In fact, only about 20% of pancreatic cancers are currently detected at an early stage.
However, a new blood test may be able to change that. Researchers at the University of California, San Diego, have developed a blood test that can detect pancreatic cancer at an early stage, when it is more treatable.
What is Pancreatic Cancer?
Pancreatic cancer is a type of cancer that starts in the cells of the pancreas, which is a glandular organ in the abdomen that produces digestive enzymes and hormones that regulate glucose metabolism.
Like other forms of cancer, pancreatic cancer begins when cells in the pancreas begin to grow and divide uncontrollably, forming a malignant tumor.
Pancreatic cancer is a particularly aggressive form of cancer, and is often not detected until it has already spread to other parts of the body. This is because the pancreas is located deep within the abdomen, making it difficult to detect early on.
Additionally, pancreatic cancer often does not cause any symptoms in its early stages, which can make it difficult to detect even with screening tests.
How is Pancreatic Cancer Currently Detected?
Currently, there are a few different ways that pancreatic cancer can be detected. However, these methods can be imperfect and often do not detect pancreatic cancer until it has reached an advanced stage.
Some of the current methods of pancreatic cancer detection include:.
: Imaging Tests
Imaging tests such as CT scans, MRIs, and ultrasounds can be used to detect pancreatic cancer. However, these tests can be expensive and are not always able to detect small tumors or early-stage cancers.
: Endoscopic Ultrasound
Endoscopic ultrasound is a type of test that involves inserting a small ultrasound probe into the mouth and down the throat, into the stomach and small intestines.
This test can be used to detect pancreatic tumors, but it can be uncomfortable and requires a specialized doctor to perform.
: Blood Tests
Currently, there are no blood tests that are widely used for the detection of pancreatic cancer. However, the new blood test developed at the University of California, San Diego, may change that.
The New Blood Test for Early Detection of Pancreatic Cancer
The new blood test for early detection of pancreatic cancer is based on the detection of a particular protein called THBS2.
This protein has been found to be present at higher levels in the blood of people with pancreatic cancer than in the blood of people without the disease.
In a study published in the journal Clinical Cancer Research, researchers tested the blood of 146 people with pancreatic cancer and 50 people without the disease.
They found that the levels of THBS2 protein were significantly higher in the blood of people with pancreatic cancer than in the blood of those without the disease.
Importantly, the blood test was also able to detect pancreatic cancer in people with early-stage disease. Of the 146 people with pancreatic cancer who were tested, the blood test was able to detect the cancer in 80% of those with stage I or II disease.
This is significant because currently, most pancreatic cancers are not detected until they have reached stage III or IV.
The blood test also had a very low false positive rate, meaning that it was unlikely to detect pancreatic cancer in people who did not have the disease.
This is important because false positives can lead to unnecessary medical procedures and anxiety for patients.
What Does This Mean for the Future of Pancreatic Cancer Detection?
If the new blood test for early detection of pancreatic cancer proves to be effective in larger clinical trials, it could have a significant impact on the survival rates of people with the disease.
Currently, the five-year survival rate for pancreatic cancer is very low, but early detection could allow for more effective treatment options and better outcomes.
Additionally, the new blood test could provide a less invasive and more cost-effective way to detect pancreatic cancer. Imaging tests and endoscopic ultrasound can be expensive and can be uncomfortable for patients.
A simple blood test could be a more accessible way for people to get screened for pancreatic cancer.
The Importance of Early Detection
The importance of early detection of pancreatic cancer cannot be overstated. Like other forms of cancer, pancreatic cancer is much more treatable when detected at an early stage.
However, because pancreatic cancer often does not cause symptoms in its early stages, it can be difficult to detect.
A blood test for early detection of pancreatic cancer could potentially save lives and improve outcomes for people with this deadly disease.
While more research is needed to confirm the effectiveness of the test, the results so far are promising and give hope for the future of pancreatic cancer detection.