Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can affect different parts of the body, including joints, skin, kidneys, and brain. It is called a “systemic” disease because it can affect any part of the body.

While SLE can occur at any age and in both sexes, it is more common in women, particularly those of childbearing age. The cause of SLE is not entirely clear though it’s believed to be a combination of genetic and environmental factors.

SLE and Dementia

A new study has been carried out recently that has linked SLE to Dementia. The study has established that people with SLE are at risk of developing dementia.

While SLE can cause various neurological symptoms such as confusion, depression, headaches, and seizures, the study findings indicate that it could also be a risk factor for developing dementia.

The research, which involved the use of medical records of 7,000 people in Northern California, indicated that people with SLE had a 40% higher likelihood of developing dementia compared to those without the disease.

The study, which was one of the largest on this topic, shows a strong link between SLE and dementia.

The Link between SLE and Dementia

The study established that SLE patients have an increased risk of dementia, but the reason for this link is not precisely known. Some of the possible explanations include:.

SLE-caused inflammation in the brain that leads to cognitive decline and eventually, dementia
SLE treatment, which includes the use of corticosteroids that might affect brain function and increase the risk of dementia
SLE itself as a risk factor for developing dementia, independent of other factors

How to reduce the Risk of Dementia in SLE patients

While the exact cause of the link is not precisely known, there are some steps that people with SLE can take to reduce the risk of dementia. They include:.

Early diagnosis and treatment of SLE to manage symptoms and reduce inflammation
Regular monitoring of cognitive function, particularly in older patients or those who have had the disease for a long time
Avoiding known dementia risk factors, such as smoking and alcohol abuse
Reducing stress and maintaining a healthy lifestyle to improve overall health

The Bottom Line

SLE is a complex disease that can affect different parts of the body, including the brain. While the exact cause of the link between SLE and dementia is not entirely known, studies show that people with SLE may be at risk of developing dementia.

However, by taking steps to manage SLE and monitoring cognitive function regularly, people with SLE can reduce the risk of developing dementia.