Cardiovascular diseases or disorders are the leading cause of morbidity and mortality throughout the world, accounting for over 30% of deaths globally. Inflammation is a key factor in the development and progression of cardiovascular diseases.
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are commonly used to manage pain and inflammation. However, some of these drugs have been associated with an increased risk of developing cardiovascular diseases. That is why researchers have been studying the use of cardio-protective pain relievers.
What are cardio-protective pain relievers?
Cardio-protective pain relievers are drugs that protect the heart and the cardiovascular system while providing pain relief.
They have been shown to reduce inflammation and minimize the risk of developing cardiovascular diseases such as coronary artery disease (CAD) and stroke.
Types of cardio-protective pain relievers
There are different types of cardio-protective pain relievers:.
Nonsteroidal anti-inflammatory drugs (NSAIDs)
NSAIDs are commonly used to manage pain and inflammation. However, some of them, such as traditional NSAIDs like ibuprofen, can increase the risk of cardiovascular diseases.
COX-2 selective inhibitors, also known as coxibs, are a type of NSAID that selectively inhibits the COX-2 enzyme and has been shown to minimize the cardiovascular risks associated with NSAIDs.
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Acetaminophen
Acetaminophen, also known as paracetamol, is another type of pain reliever that has been shown to be cardio-protective.
Unlike NSAIDs, acetaminophen does not have anti-inflammatory properties, but it does have antioxidant and antiplatelet effects that can benefit the cardiovascular system.
Aspirin
Aspirin, or acetylsalicylic acid, is a non-steroidal anti-inflammatory drug that is commonly used to manage pain, fever and inflammation. However, in lower doses, aspirin has been shown to be cardio-protective.
It inhibits platelet aggregation and reduces the risk of cardiovascular events such as heart attacks and strokes.
Omega-3 fatty acids
Omega-3 fatty acids are essential fatty acids that can be found in fish oil and other sources. They have anti-inflammatory properties and have been shown to reduce the risk of cardiovascular diseases such as heart attacks and strokes.
Conclusion
Cardio-protective pain relievers are drugs that can provide pain relief while protecting the heart and the cardiovascular system.
Different types of cardio-protective pain relievers include COX-2 selective inhibitors, acetaminophen, aspirin, and omega-3 fatty acids. These drugs have been shown to reduce inflammation and minimize the risk of developing cardiovascular diseases such as CAD and stroke.
