Corticosteroids are a type of medication that is used to treat a wide range of conditions, from asthma to autoimmune diseases. While they can be effective at managing these conditions, they can also cause a number of unwelcome side effects.

Some of the most common corticosteroid side effects include weight gain, mood swings, increased appetite, and weakened bones. Fortunately, there is a medication available that can help mitigate some of these side effects. This medication is known as bisphosphonates.

What are bisphosphonates?

Bisphosphonates are a type of medication that is used primarily to treat bone conditions such as osteoporosis and Paget’s disease.

They work by slowing down the rate at which bones break down, which can help strengthen bones and reduce the risk of fractures. However, bisphosphonates also have another important use: mitigating the side effects of corticosteroids.

How do bisphosphonates help with corticosteroid side effects?

Bisphosphonates are effective at mitigating some of the most common corticosteroid side effects, particularly those related to bone health. When taken alongside corticosteroids, bisphosphonates can help reduce the risk of osteoporosis and fractures.

In addition, they can help decrease bone pain and improve bone density.

Bisphosphonates can also be helpful in reducing some of the other side effects of corticosteroids, such as weight gain.

While weight gain is often a result of increased appetite and fluid retention, bisphosphonates can help counteract this by improving insulin sensitivity. This can help reduce the amount of fat that is stored in the body, which can in turn reduce weight gain.

What are some common bisphosphonates?

There are several different bisphosphonates available, each with its own unique properties and uses. Some of the most commonly prescribed bisphosphonates include:.

Alendronate (brand name Fosamax)
Risedronate (brand name Actonel)
Ibandronate (brand name Boniva)
Zoledronic acid (brand name Reclast, Zometa)

What are some potential side effects of bisphosphonates?

While bisphosphonates can be effective at reducing corticosteroid side effects, they do come with their own set of potential side effects. Some of the most common side effects of bisphosphonates include:.

Gastrointestinal problems, such as stomach upset and diarrhea
Bone, joint, or muscle pain
Headaches
Difficulty swallowing
Irregular heartbeat

In rare cases, bisphosphonates can also cause more serious side effects, such as osteonecrosis of the jaw or an atypical fracture of the femur.

However, these side effects are relatively uncommon and tend to occur only with long-term use of bisphosphonates.

Conclusion

If you are taking corticosteroids and are experiencing side effects such as weight gain or weakened bones, bisphosphonates may be a helpful addition to your treatment plan.

While they do come with their own set of potential side effects, they can be effective at mitigating the side effects of corticosteroids and improving bone health. Talk to your doctor to see if bisphosphonates may be right for you.