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Breakthrough treatments for psoriatic arthritis and spondylarthritis

Breakthrough treatments such as biologics, tsDMARDs, and JAK inhibitors offer hope for people with psoriatic arthritis and spondylarthritis. Physical therapy, dietary changes, and weight management can also play a role in managing symptoms and preventing joint damage
Breakthrough treatments for psoriatic arthritis and spondylarthritis

Psoriatic arthritis and spondylarthritis are two types of chronic inflammatory arthritis that can cause debilitating pain and joint damage. Psoriatic arthritis is a type of arthritis that affects some people with psoriasis, an autoimmune skin condition.

Spondylarthritis is an umbrella term used to describe a group of related inflammatory conditions that primarily affect the spine and joints in the pelvis.

Both types of arthritis can cause severe pain, stiffness, swelling, and fatigue. They can also lead to irreversible joint damage, disability, and other serious health complications.

While there is no cure for psoriatic arthritis or spondylarthritis, there are several breakthrough treatments that can help manage symptoms and improve quality of life.

1. Biologic Therapies

Biologic therapies are medications that target specific molecules in the immune system that contribute to inflammation.

They are usually given by injection or infusion and are designed to block the activity of certain proteins that trigger inflammation and joint damage. Biologics have revolutionized the treatment of psoriatic arthritis and spondylarthritis and have significantly improved outcomes for many patients.

Some examples of biologic therapies used to treat psoriatic arthritis and spondylarthritis are:.

  • Adalimumab (Humira)
  • Etanercept (Enbrel)
  • Infliximab (Remicade)
  • Golimumab (Simponi)
  • Secukinumab (Cosentyx)
  • Ixekizumab (Taltz)

2. Targeted Synthetic Disease-Modifying Anti-Rheumatic Drugs (tsDMARDs)

Targeted synthetic disease-modifying anti-rheumatic drugs (tsDMARDs) are another class of medications that have revolutionized the treatment of psoriatic arthritis and spondylarthritis.

They are oral medications that work by blocking specific enzymes that contribute to inflammation. TsDMARDs are less expensive and more convenient than biologics and may be a good option for some patients who cannot tolerate biologics.

Some examples of tsDMARDs used to treat psoriatic arthritis and spondylarthritis are:.

  • Methotrexate
  • Leflunomide
  • Apremilast

3. Janus Kinase (JAK) Inhibitors

Janus kinase (JAK) inhibitors are a newer class of medications that have shown promising results in the treatment of psoriatic arthritis and spondylarthritis.

They work by inhibiting the activity of Janus kinase enzymes, which are involved in the inflammatory process. JAK inhibitors are oral medications that may offer an alternative to biologics and tsDMARDs for some patients.

Some examples of JAK inhibitors used to treat psoriatic arthritis and spondylarthritis are:.

  • Tofacitinib (Xeljanz)
  • Baricitinib (Olumiant)

4. Physical Therapy and Exercise

Physical therapy and exercise can help improve joint mobility, reduce pain and stiffness, and prevent joint damage in people with psoriatic arthritis and spondylarthritis.

Related Article Revolutionary advances in psoriatic arthritis and spondylarthritis treatments Revolutionary advances in psoriatic arthritis and spondylarthritis treatments

Physical therapists can design personalized exercise programs that take into account the patient’s specific condition and symptoms. Exercise can also help improve overall health, reduce fatigue, and boost mood.

5. Dietary Changes and Weight Management

Dietary changes and weight management can also play an important role in managing psoriatic arthritis and spondylarthritis.

Eating a healthy diet rich in anti-inflammatory nutrients such as fruits, vegetables, and omega-3 fatty acids may help reduce inflammation and improve symptoms. Losing weight can also ease joint pain and reduce the risk of joint damage.

6. Surgery

In some cases, surgery may be necessary to repair or replace damaged joints in people with psoriatic arthritis or spondylarthritis. Joint replacement surgery is a common procedure for severe cases of joint damage, particularly in the hips and knees.

Surgery is typically reserved for cases where other treatments have failed or are no longer effective.

7. Complementary and Alternative Therapies

Complementary and alternative therapies such as acupuncture, massage, and herbal supplements may offer additional relief for some people with psoriatic arthritis and spondylarthritis.

However, it is important to talk to a healthcare provider before trying any new therapies or supplements, as some may interact with medications or pose a risk for certain patients.

8. Patient Education and Support

Education and support are also key components of managing psoriatic arthritis and spondylarthritis. Learning about the condition and its treatment options can help patients make informed decisions about their care and better advocate for themselves.

Support groups and online forums can also provide a sense of community and emotional support for people with these conditions.

9. Early Detection and Treatment

Early detection and treatment of psoriatic arthritis and spondylarthritis is critical to prevent joint damage and other complications.

It is important for patients with psoriasis or other autoimmune conditions to be screened regularly for signs of joint inflammation, even if they do not yet have symptoms. Early treatment with biologics, tsDMARDs, or other medications may help slow or halt the progression of joint damage.

10. Integrative Medicine and Mind-Body Therapies

Integrative medicine and mind-body therapies such as yoga, meditation, and tai chi may also offer additional benefits for people with psoriatic arthritis and spondylarthritis.

These practices can help reduce stress, improve relaxation, and promote overall well-being. They may also help reduce pain and inflammation by calming the nervous system and reducing the production of stress hormones.

Disclaimer: This article serves as general information and should not be considered medical advice. Consult a healthcare professional for personalized guidance. Individual circumstances may vary.
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