Multiple Sclerosis is a chronic autoimmune disease involving the nervous system. It affects the spinal cord, brain, and optic nerves.
The condition is primarily characterized by the inflammation of the protective sheath that covers nerve fibers in the brain and spinal cord, which leads to communication issues between the body and the brain. The symptoms of MS can range from mild to severe and include numbness and tingling, muscle weakness, fatigue, vision problems, and loss of coordination.
Causes of Multiple Sclerosis
Different factors have been found to contribute to Multiple Sclerosis. These include environmental, genetic, and immunologic factors.
Genetic susceptibility is a significant cause of MS, as studies have shown that individuals with a family history of MS have an increased risk of developing the condition. Besides, studies have shown that individuals who live in regions with less exposure to sunlight or vitamin D are more likely to develop MS than individuals living in regions with more exposure to sunlight.
Can Vitamin D Supplementation Improve Multiple Sclerosis Outcomes
Vitamin D deficiency or insufficiency has, without a doubt, been linked to the development and progression of MS. There is a high prevalence of vitamin D deficiency in MS patients, particularly during the winter months.
In addition, people diagnosed with Multiple Sclerosis have lower serum vitamin D levels than those without the disease, indicating a clear association between the two.
The precise mechanism by which vitamin D affects MS outcomes is unclear. However, studies have pointed to the role of vitamin D in regulating the immune system and preventing inflammation and autoimmune responses.
A study conducted in 2017 sought to determine the role of vitamin D supplementation in reducing the severity of MS symptoms. A total of 40 patients diagnosed with Multiple Sclerosis were treated with 50,000 IU of vitamin D or a placebo over 12 weeks.
The study found that the serum vitamin D levels increased significantly in the group treated with vitamin D, while those treated with placebo had no significant changes. Besides, patients treated with vitamin D had a significant reduction in the severity of MS symptoms, including a decrease in the number of relapses.
Another study in 2019 assessed the impact of vitamin D supplementation on the quality of life of MS patients. The study involved 60 patients who were divided into two groups.
One group received 50,000 IU of vitamin D weekly, while the other group received a placebo for twelve weeks. The patients treated with vitamin D showed significant improvements in all measures of quality of life, including fatigue, depression, anxiety, and reduced muscle strength, compared to the placebo group.
The study concluded that vitamin D supplementation improves the quality of life of MS patients and should be considered as part of standard care.
Conclusion
Studies have shown that vitamin D supplementation can significantly improve the outcomes of Multiple Sclerosis. Vitamin D supplements have been shown to reduce the severity of MS symptoms and improve the quality of life of patients.
Besides, vitamin D has also been linked to a lower prevalence of disease relapse and fewer occurrences of new brain lesions. Hence, individuals diagnosed with MS should ensure that they get sufficient vitamin D through diet and supplements.