Rheumatoid Arthritis (RA) is a chronic autoimmune disease that affects the joints, particularly the hands, knees, and feet.

It is a debilitating condition that may lessen the quality of life as the inflammation causes pain, stiffness, swelling, and loss of mobility. Although there is no cure for RA, it is possible to manage the symptoms, which can be done through managing inflammation, exercise, and diet. In this article, we will explore the role of probiotics in managing rheumatoid arthritis symptoms.

What are probiotics?

Probiotics are live microorganisms that are beneficial for the body, especially the digestive system.

They are known as “good” bacteria as they help to counteract harmful bacteria that may be present in the gut, resulting in a healthy balance of microorganisms. Probiotics are commonly found in fermented foods such as yogurt, kefir, kimchi, and sauerkraut. Probiotics can also be consumed through supplements.

The link between gut microbiome and rheumatoid arthritis

The gut microbiome, which is the collection of microorganisms in the gut, has been found to have an influence on the immune system.

The gut microbiome communicates with the immune system, and when there is an imbalance in the gut microbiome, it may lead to the development of autoimmune diseases such as RA. The link between the gut microbiome and RA has been researched, and there is evidence that suggests that the dysbiosis or imbalance of the gut microbiome may play a role in the development of RA.

How probiotics can help manage rheumatoid arthritis symptoms

Probiotics have been found to modulate the immune response, reduce inflammation, and affect pain perception. In RA patients, taking probiotics may help in managing the symptoms of the disease, and in reducing the severity of the condition.

Reducing inflammation

Chronic inflammation is a hallmark of RA, and it is known to be the root cause of joint damage.

Studies have shown that certain strains of probiotics may help to reduce inflammation by lowering the levels of inflammatory markers such as C-reactive protein (CRP) and interleukin-6 (IL-6). Probiotics can also help to improve gut barrier function, which may reduce inflammation in the body by reducing the exposure of the immune system to harmful substances in the gut.

Modulating the immune system

The immune system of RA patients is overactive, leading to an increased production of pro-inflammatory cytokines. Probiotics can help by modulating the immune system, which leads to a reduction in the production of pro-inflammatory cytokines.

Lactobacillus acidophilus, Bifidobacterium bifidum, and Streptococcus thermophilus are some of the strains that have been found to have an immunomodulatory effect.

Decreasing pain

RA patients often suffer from joint pain and discomfort that can be debilitating. Probiotics can help to reduce pain by modulating the perception of pain.

Studies have shown that the administration of Lactobacillus casei Shirota and Bifidobacterium lactis BB-12 improved pain perception in patients with knee osteoarthritis.

Choosing the right probiotic strains for managing RA symptoms

When selecting probiotics for managing RA symptoms, it is important to choose strains that have been particularly researched for this purpose. Some of the strains that have been found to be effective include:.

Lactobacillus acidophilus
Bifidobacterium bifidum
Bifidobacterium lactis BB-12
Streptococcus thermophilus
Lactobacillus casei Shirota

It is also important to note that the effects of probiotics may vary from individual to individual, and it may take some time before the benefits of probiotics are evident.

Conclusion

Probiotics have been found to be effective in managing RA symptoms, particularly in reducing inflammation, modulating the immune system, and reducing pain perception.

While probiotics alone cannot cure RA, they can significantly improve the quality of life for RA patients. If you are considering taking probiotics as a part of managing your RA, it is important to consult your physician first to discuss if there are any potential risks, or to determine the best strains that may work for you.