Glioblastoma is a type of brain tumor that develops in the supportive tissues of the brain. It is a very aggressive type of cancer that can be fatal. Glioblastomas are the most common type of brain cancer, accounting for about 47% of all brain tumors.
What Causes Glioblastoma?
The specific cause of glioblastoma is still unknown, but research has shown that it may be caused by a combination of genetic and environmental factors. Some of the risk factors for glioblastoma include:.
- Age: Glioblastoma is more common in people over the age of 50.
- Gender: Men are more likely to develop glioblastoma than women.
- Exposure to radiation: This includes exposure to radiation during cancer treatment or from other sources, such as radiation therapy for other conditions.
- Exposure to chemicals: Some chemicals, such as pesticides, have been linked to an increased risk of glioblastoma.
Symptoms of Glioblastoma
The symptoms of glioblastoma can vary depending on where the tumor is located in the brain. Some common symptoms include:.
- Headaches
- Nausea and vomiting
- Changes in vision or hearing
- Seizures
- Difficulty speaking or understanding language
- Changes in behavior or personality
- Loss of coordination or balance
Diagnosis of Glioblastoma
Diagnosing glioblastoma involves a number of different tests and procedures, including:.
- Neurological exam: This exam involves testing reflexes, muscle strength, and coordination.
- Imaging tests: This may include CT scans, MRI scans, and PET scans to get a better view of the brain and any tumors.
- Biopsy: A small sample of tissue from the tumor is taken and examined under a microscope to determine the type of cells present and the grade of the tumor.
Treatment for Glioblastoma
Treatment for glioblastoma typically involves surgery, radiation therapy, and chemotherapy. The goals of treatment are to remove as much of the tumor as possible, destroy any remaining cancer cells, and slow the growth of the tumor.
- Surgery: This involves removing as much of the tumor as possible. In some cases, the entire tumor may not be able to be removed because it is too close to important parts of the brain.
- Radiation therapy: This involves using high-energy radiation to destroy cancer cells. Radiation therapy may be used before or after surgery.
- Chemotherapy: This involves using drugs to kill cancer cells. Chemotherapy may be given orally or through an IV.
The Lethality of Glioblastoma
Glioblastoma is a very aggressive type of brain cancer, and as such, it is very lethal. The survival rates for glioblastoma are low, with most people living for only about 15 months after diagnosis.
Only about 5% of people with glioblastoma survive for five years or more.
The lethality of glioblastoma is due to a number of factors, including:.
- The location of the tumor: Glioblastomas are often located in areas of the brain that are important for vital functions such as breathing and heart rate. This means that surgery to remove the tumor may not be possible.
- The invasive nature of the tumor: Glioblastomas are highly invasive, meaning that they spread throughout the brain tissue quickly and are difficult to remove completely.
- The resistance of the tumor to treatment: Glioblastomas are often resistant to radiation therapy and chemotherapy, making it difficult to destroy all of the cancer cells.
Living with Glioblastoma
Living with glioblastoma can be challenging, both for the person with the cancer and their loved ones. It is important to work closely with doctors to manage symptoms and side effects of treatment.
In addition to medical treatment, there are a number of support services available to help people with glioblastoma and their families, including support groups and counseling.
Conclusion
Glioblastoma is a very aggressive type of brain cancer that is difficult to treat. Although there is no known cure for glioblastoma, there are treatments available that can help to slow the growth of the tumor and manage symptoms.
It is important for people with glioblastoma and their families to work closely with doctors and take advantage of the available support services.