A neurinoma, also known as a schwannoma, is a benign tumor that affects the cells of the nerve sheaths (Schwann cells). These tumors grow slowly and usually manifest in the head, neck, and other areas of the nervous system.
Types of Neurinoma
There are several types of neurinoma:.
1. Acoustic Neuroma (Vestibular Schwannoma)
This is the most common type of neurinoma. It develops in the vestibular nerve which connects the inner ear to the brain. It is usually slow-growing and non-cancerous.
2. Trigeminal Schwannoma
This type of neurinoma affects the tri-partite nerve which connects the face and neck to the brain. It commonly affects people with neurofibromatosis type 2 (NF2).
3. Spinal Schwannoma
These tumors develop in the spinal cord or along peripheral nerves. They can put pressure on the spinal cord or nerve roots and cause symptoms such as pain, numbness, and weakness.
What Causes Neurinoma?
Despite their prevalence, the exact cause of neurinoma remains unknown. However, studies have suggested the following factors may contribute to their development:.
1. Genetics
Some people may inherit a predisposition for developing schwannomas. Neurofibromatosis type 2 (NF2) is one of the inherited conditions associated with the development of schwannomas.
2. Exposure to Radiation
People exposed to high doses of radiation may develop neurinomas. Exposure to nuclear fallout or radiation therapy used to treat certain types of cancer may increase the risk of developing neurinoma.
3. Age
The incidence of neurinoma increases with age, with most cases occurring in individuals over the age of 50.
4. Hormonal Imbalance
Research has suggested that excessive estrogen exposure may increase the risk of developing neurinoma. A study found that women using hormone replacement therapy (HRT) were at a higher risk of developing acoustic neuroma.
5. Environmental Toxins
Preliminary studies have suggested that exposure to certain environmental toxins, such as those found in pesticides and industrial chemicals, may increase the risk of developing neurinoma.
Treatment for Neurinoma
Most neurinomas are slow-growing and non-cancerous, and as such, they may not require treatment unless they are causing symptoms or are growing. Treatment options include:.
1. Observation
If a neurinoma is not causing symptoms, it may be monitored closely through periodic imaging tests from an MRI, CT, or PET scan, to monitor growth of the tumor.
2. Surgery
If the tumor is causing significant symptoms or is growing, surgery may be recommended. During surgery, the tumor is removed while preserving the function of the affected nerve.
3. Radiation Therapy
Radiation therapy may be used to shrink the tumor in patients who are not good candidates for surgery, or if the tumor is too large or in a difficult location.
Conclusion
While the exact cause of neurinoma remains unknown, several factors are believed to contribute to their development. Early detection, accurate diagnosis, and treatment are key to managing the disease and improving outcomes.