When we think of IVF (in vitro fertilization), we often focus solely on the female partner’s age as a determining factor in the success of the treatment.
However, studies have shown that the male partner’s age also plays a significant role in IVF success.
Sperm Quality and Quantity
As men age, the quality and quantity of their sperm can decline. This can affect the success of IVF treatments because it takes a healthy and viable sperm to fertilize an egg in vitro.
A recent study found that men over the age of 35 produced significantly less sperm than younger men, and the sperm they did produce was more likely to have DNA damage.
Chromosomal Abnormalities
Advanced paternal age has been linked to an increased risk of chromosomal abnormalities in offspring. This is because sperm cells continue to divide and replicate throughout a man’s life, and each replication comes with a risk of a genetic mutation.
As men age, the risk of these mutations increases, which can lead to chromosomal abnormalities in their offspring.
Lower Pregnancy Rates
Studies have shown that male age is strongly correlated with lower pregnancy rates in IVF treatments.
One study found that women who were undergoing IVF with male partners over the age of 40 had significantly lower pregnancy rates than women with partners under the age of 30. It is believed that this is due to the decline in sperm quality and quantity as men age.
Increased Risk of Miscarriage
As we’ve seen, advanced paternal age can lead to chromosomal abnormalities in offspring. These abnormalities are linked to a higher risk of miscarriage.
A study of over 50,000 IVF pregnancies found that the risk of miscarriage was higher when the male partner was over the age of 40.
The Importance of Male Fertility Testing
Given the role that male age can play in the success of IVF treatments, it is important that male partners undergo fertility testing before beginning treatment.
This testing can help identify any potential issues with sperm count, motility, or morphology, as well as any genetic mutations or chromosomal abnormalities. Identifying these issues early on can help doctors better tailor IVF treatments to the couple’s specific needs.
Conclusion
When it comes to IVF success, male age is a critical factor that should not be overlooked.
Advanced paternal age can lead to a variety of issues that can decrease the chances of a successful IVF treatment, including decreased sperm quality and quantity, an increased risk of chromosomal abnormalities, lower pregnancy rates, and a higher risk of miscarriage. To increase the chances of success, it is important that male partners undergo fertility testing before beginning treatment.