Cholesterol is a waxy, fat-like substance that is present in every cell of our body.
It is an essential component of our cell membranes and helps in the production of hormones, vitamin D, and bile acids, which is why it is important to have some cholesterol in our body. However, high levels of cholesterol in the blood can lead to several health problems, including heart diseases, stroke, and even cancer.
What is cholesterol?
Cholesterol is a type of lipid or fat that is produced by our liver and is found in certain foods such as meat, eggs, and dairy products.
Cholesterol travels through our blood in small packages called lipoproteins, which are made up of fats and proteins.
There are two types of lipoproteins – low-density lipoprotein (LDL) or “bad” cholesterol and high-density lipoprotein (HDL) or “good” cholesterol.
LDL carries cholesterol from the liver to the cells in our body, whereas HDL removes excess cholesterol from the bloodstream and transports it back to the liver to be expelled from the body.
Cholesterol and Cancer
Several studies have shown that high levels of LDL or “bad” cholesterol are linked to an increased risk of cancer. In fact, some studies suggest that cholesterol fuels the growth and spread of cancer cells.
Cancer cells require cholesterol to grow and divide. Cholesterol is essential for cancer cells to maintain their cell membrane and to form new cell membranes required for tumour growth.
In addition, cholesterol also fuels the production of proteins that are required for the survival and growth of cancer cells.
Recent studies have suggested that targeting cholesterol metabolism in cancer cells might be an effective strategy to control cancer growth and progression.
The Link between Cholesterol and Breast Cancer
Breast cancer is one of the most common types of cancer in women worldwide. The risk of developing breast cancer increases with age, family history of breast cancer, and high levels of estrogen.
Recent studies have suggested that high levels of cholesterol can also increase the risk of breast cancer.
A study conducted on more than 15,000 women found that those with high levels of LDL cholesterol were at a higher risk of developing breast cancer.
In addition, women who reduced their cholesterol levels with statins had a reduced risk of breast cancer.
Another study conducted on mice found that reducing cholesterol levels may prevent the spread of breast cancer to other parts of the body.
The Link between Cholesterol and Prostate Cancer
Prostate cancer is the most common type of cancer in men, and the second leading cause of cancer-related deaths in men worldwide.
Studies have shown that men with high levels of cholesterol are more likely to develop prostate cancer, and those with low levels of HDL or “good” cholesterol have a higher risk of developing aggressive prostate cancer.
One study found that men who had high levels of cholesterol in their blood were more likely to experience prostate cancer recurrence after treatment than those with lower cholesterol levels.
The Link between Cholesterol and Colon Cancer
Colon cancer is the third most common type of cancer worldwide, and it develops in the colon or the rectum. Several studies have suggested that high levels of cholesterol may increase the risk of colon cancer.
One study conducted on more than 28,000 women found that those with high levels of cholesterol were at an increased risk of developing colon cancer.
Another study conducted on men found that those with a high BMI and high cholesterol levels had an increased risk of developing colon cancer.
Furthermore, studies have shown that reducing cholesterol levels may help prevent the development of colon cancer.
The Link between Cholesterol and Lung Cancer
Lung cancer is one of the most common types of cancer worldwide, and it accounts for the largest number of cancer-related deaths. Studies have suggested that high levels of cholesterol may increase the risk of lung cancer.
A study conducted on more than 3,500 people found that those with high levels of LDL cholesterol were at a higher risk of developing lung cancer. Another study found that reducing cholesterol levels with statins may reduce the risk of lung cancer.
The Link between Cholesterol and Skin Cancer
Skin cancer is the most common type of cancer in the United States, and it is caused by ultraviolet (UV) radiation from the sun. Studies have suggested that high levels of cholesterol may increase the risk of skin cancer.
One study conducted on more than 60,000 women found that those with high levels of cholesterol were at an increased risk of developing skin cancer. Another study found that reducing cholesterol levels with statins may decrease the risk of skin cancer.
Conclusion
The link between high levels of cholesterol and an increased risk of cancer is becoming increasingly clear.
Several studies have shown that cholesterol fuels the growth and spread of cancer cells, and reducing cholesterol levels may help prevent the development and spread of cancer.