Tecovirimat, also known as Tpoxx, is an antiviral medication that has been approved by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA).

It is used to treat smallpox, a highly contagious disease caused by the Variola virus. The use of tecovirimat is limited to individuals who are at high risk of contracting smallpox, such as laboratory workers, military personnel, and healthcare workers.

How Does Tecovirimat Work?

Tecovirimat works by inhibiting the production of viral DNA in infected cells, which prevents the virus from replicating and spreading throughout the body.

It specifically targets the orthopoxvirus family, which includes the Variola virus that causes smallpox.

What Are the Dosages of Tecovirimat?

The recommended dosage of tecovirimat is 600 mg twice daily for 14 days. The medication should be taken with food to increase its absorption. It is available in capsule form and should be swallowed whole with a glass of water.

What Are the Side Effects of Tecovirimat?

The most common side effects of tecovirimat include headaches, nausea, fatigue, and diarrhea. In rare cases, patients may experience more serious side effects, such as liver damage, allergic reactions, and seizures.

If you experience any of these symptoms while taking tecovirimat, you should contact your healthcare provider immediately.

Who Should Not Take Tecovirimat?

Tecovirimat should not be taken by individuals who have a known allergy to the medication or any of its ingredients. It should also not be taken by individuals who have liver disease or a history of liver problems.

Women who are pregnant or breastfeeding should consult with their healthcare provider before taking tecovirimat.

How Is Tecovirimat Stored?

Tecovirimat should be stored at room temperature (between 68°F and 77°F) in its original container. It should be kept away from light and moisture.

What Should I Do if I Miss a Dose of Tecovirimat?

If you miss a dose of tecovirimat, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

Can Tecovirimat Be Used to Prevent Smallpox?

Tecovirimat is not recommended for use as a preventive measure against smallpox. Instead, the best way to prevent smallpox is through vaccination. The smallpox vaccine is highly effective and provides long-lasting immunity against the virus.

Individuals who are at high risk of contracting smallpox should consider getting vaccinated.

Conclusion

Tecovirimat is an antiviral medication that is used to treat smallpox in individuals who are at high risk of contracting the disease.

It works by inhibiting the production of viral DNA in infected cells, preventing the virus from replicating and spreading throughout the body. The medication is available in capsule form and is taken twice daily with food. While tecovirimat is generally safe, patients may experience side effects such as headaches, nausea, and diarrhea.

Individuals who are allergic to the medication or have liver disease should not take tecovirimat. It is not recommended as a preventive measure against smallpox, as vaccination is the most effective way to protect against the disease.